Inflammation of the liver caused by infection with HCV is referred to as hepatitis C.
- If the inflammation is not reversed, it becomes chronic (ongoing, long term) and can cause chronic liver disease, which can be serious or even fatal.
- At least 75% of people infected with hepatitis C develop chronic hepatitis C.
- If the disease progresses to the point at which the liver begins to fail (end stage liver disease), the only treatment is liver transplantation.
- HCV is one of the most common causes of chronic liver disease in the United States and the most common cause of chronic viral hepatitis.
- It is believed to be the cause of about 15-20% of all cases of acute (new, short term) viral hepatitis and half of all cases of cirrhosis, end-stage liver disease, and liver cancer.

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